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Pyridoxamine for menopausal disorder

Phase 2
Recruiting
Conditions
menopausal disorder with psychological symptoms
Registration Number
JPRN-jRCTs031220256
Lead Sponsor
Terauchi Masakazu
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Female
Target Recruitment
50
Inclusion Criteria

[provisional registration]
Those who fulfill all the items below will be registered provisionally:
1. those who have menopausal disorder with psychological symptoms by main doctor(excluding those who have symptoms due to cancer treatment)
2. those who responded as either moderate or severe to any of the MHR-QOL items: #10 I feel less enthusiastic about things than before.; #11 Things I used to enjoy have become a bit of chore.; #12 I do less than I would like.; #16 I upset about small things.; #17 I feel nervous about small things.
3. those who are aged 40 to 64 years old
4. out-clinic patients
5. female
6. those how are able to provide informed consent
[definite registration]
Those who fulfill the inclusion criteria item #2 after 2 weeks of placebo administration will be registered definitely.

Exclusion Criteria

Those who fulfill any of the items below will be excluded from the trial.
1. those who have depressive disorders not related to menopause
2. those who have serious comorbidities, such as cancers, cardiac diseases, liver diseases, hematologic diseases, etc.
3.those who were enrolled in another trial less than three months ago, or those who are going to be enrolled in another trial during the course of the current one
4. those who were prescribed any of the incompatible drugs (estrogens, Kampo formulae, psychotropic agents, etc.) within the past 4 weeks
5. those who have serious drug allergy
6. those whose eGFR are less than 30 mL/min
7. those whom the principal investigator or co-investigators consider to be incompatible

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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