Evaluation of the effect of curcumin in the prevention of vancomycin-induced nephrotoxicity in patients hospitalized in the intensive care unit of Kosar Hospital, Semnan: a randomized, double-blinded, placebo-controlled clinical trial
Phase 3
Not yet recruiting
- Conditions
- Acute kidney failure.Acute kidney failure, unspecifiedN17.9
- Registration Number
- IRCT20240501061620N1
- Lead Sponsor
- Semnan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
Patients aged 18-65, receiving vancomycin
Creatinine clearance > 45 ml/min
Exclusion Criteria
Proteinuria and/or hematuria, acute kidney injury or any underlying renal disorder
Sepsis
Sever liver disease
Sever and active bleeding
Receiving any other nephrotoxic drug
Receiving anticoagulant drugs at therapeutic doses or receiving warfarin
Receiving antioxidant supplements
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method