Role of home telemonitoring of lung function using the forced oscillation technique in predicting exacerbations and control among moderate-severe asthmatics during stable treatment: a pragmatic, observational study

Sydney Medical School, University of Sydney0 sites60 target enrollmentMay 18, 2018

Overview

No summary available.

Registry

who.int

Start Date

May 18, 2018

End Date

TBD

Last Updated

7 years ago

Study Type

Observational

Sex

All

Sponsor

Sydney Medical School, University of Sydney

•Inclusion Criteria:
•above 18 years of age,
•diagnosis of asthma, confirmed by written report from a physician, and
•receiving maintenance asthma treatment at at least Step 4 (on moderate to high dose of ICS (budesonide \>500 mcg/day or fluticasone propionate \>200 mcg/day or equivalent and LABA treatment) of Australian guidelines, and
•ACQ\-5 score \>\=1\.5, indicating suboptimal asthma symptom control.
•All patients will be eligible if they are taking maximal inhaled therapy (high dose ICS/LABA with or without other add\-on therapy) and have at least one of the following additional risk factors for poor asthma outcomes or exacerbation's, i.e.: at least one severe exacerbation in the past 12 months, low FEV1 (\<60% predicted), obesity (BMI \>\=30\), and in addition, the treating physician considers that there is no immediate indication for stepping up treatment. For example, this decision may be made by the treating physician if the risks of further stepping up treatment outweigh the potential benefit, if alternative non\-biologic therapies have already been tried, or if the patient does not satisfy PBS criteria for a biological therapy.

•any other confounding major disease or condition as deemed appropriate by investigator, determined by review of medical history and/or patient reported medical history, and
•impaired ability to understand instructions or perform FOT unsupervised.