Pragmatic, Randomized Evaluation of Statin Active Choice to Reach Improved Outcomes Based on Evidence

Not Applicable

Completed

• Conditions: Cardiovascular Diseases
• Interventions: Behavioral: Active choice; Behavioral: Social comparison feedback

• Registration Number: NCT03021759
• Lead Sponsor: University of Pennsylvania

Brief Summary

In this study, the investigators will conduct a pragmatic, cluster-randomized, controlled trial to evaluate an active choice intervention with and without social comparison feedback to increase physician statin prescribing rates for eligible patients.

Detailed Description

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the United States. Strong evidence indicates that statin medications can reduce the risk of CVD and for those with CVD statins have been shown to reduce mortality. Despite this evidence, statins are under-prescribed. In this study, the investigators will test the effectiveness of nudges targeted to physicians using active choice and social comparisons feedback to increasing the rate at which statin medications are prescribed to patients eligible based on national practice guidelines.

Study Timeline

• Study First Submitted: 2017-01-12
• Study First Submitted QC: 2017-01-13
• Study First Posted: 2017-01-16
• Study Start: 2017-02-21
• Primary Completion: 2017-04-21
• Study Completion: 2017-04-21
• Results First Submitted: 2018-10-30
• Status Verified: 2019-03
• Results First Submitted QC: 2019-03-20
• Last Update Submitted: 2019-03-20
• Results First Posted: 2019-06-20
• Last Update Posted: 2019-06-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 4774

Inclusion Criteria

• Patient has a primary care physician at University of Pennsylvania Health System
• Patient meets 2013 AHA/ACC guidelines for statin therapy but no record of a statin prescription in the electronic health record

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Exclusion Criteria

• Patient has an allergy or adverse reaction to statins documented in the electronic health record
• Patient has glomerular filtration rate less than 30 mL/min
• Physicians (and their respective patients) will be excluded if they have less than 10 patients among their entire panel that are eligible for a statin

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Active choice with social comparison feedback	Active choice	Physicians will be asked to review a list of their patients eligible for statin therapy who are not yet prescribed a statin and make an active choice whether or not to prescribe a statin. Physicians will receive social comparison feedback informing them of how their performance compares to their peers
Active choice with social comparison feedback	Social comparison feedback	Physicians will be asked to review a list of their patients eligible for statin therapy who are not yet prescribed a statin and make an active choice whether or not to prescribe a statin. Physicians will receive social comparison feedback informing them of how their performance compares to their peers
Active choice	Active choice	Physicians will be asked to review a list of their patients eligible for statin therapy who are not yet prescribed a statin and make an active choice whether or not to prescribe a statin.

Primary Outcome Measures

Name	Time	Method
Statin Prescribing Rate	Two Months	Percentage of patients eligible for a statin that have been prescribed a statin

Trial Locations

Locations (1)

University of Pennsylvania Health System; 🇺🇸 Philadelphia, Pennsylvania, United States