Spectral CT in Radiotherapy for Cervical Cancer

Recruiting

• Conditions: Cervical Cancer; Radiotherapy

• Registration Number: NCT06433817
• Lead Sponsor: Peking Union Medical College Hospital

Brief Summary

The purpose of this study was to explore the potential application of spectral CT for radiotherapy in cervical cancer.

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-05
• Study First Submitted: 2024-05-08
• Study Start: 2024-05-22
• Study First Submitted QC: 2024-05-27
• Last Update Submitted: 2024-05-27
• Study First Posted: 2024-05-30
• Last Update Posted: 2024-05-30
• Primary Completion: 2026-05-22
• Study Completion: 2026-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 150

Inclusion Criteria

1. All patients were confirmed cervical cancer by pathology
2. patients were treated with concurrent chemoradiotherapy
3. Spectral CT scans acquisition performed during the arterial phase and venous phase
4. All the patients underwent a 18F-FDG PET/CT before treatment

Exclusion Criteria

1. CT without spectral scans
2. History of allergy to intravenous contrast
3. Pregnant or potentially pregnant female subjects

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison of spectral CT derived data with response evaluation in cervical cancer	through study completion, an average of 2 year	To evaluate the tumor response of using quantitative parameters in spectral CT for cervical cancer patients according to RECIST 1.1

Secondary Outcome Measures

Name	Time	Method
Application of energy spectrum CT in brachytherapy of cervical cancer	through study completion, an average of 2 year	The ability to reduce metal artifact and assist in target delineation
Identifying metastatic lymph nodes in cervical cancer with spectral CT	through study completion, an average of 2 year	To evaluate the diagnostic performances of using spectral CT for identifying metastatic lymph nodes in patients with cervical cancer

Trial Locations

Locations (1)

Peking Union Medical College Hospital; 🇨🇳 Beijing, Beijing, China