Systematic Assessment of Competitive Flow in Coronary Artery Bypass Grafts by Wave Intensity Analysis

Imperial College London1 site in 1 country40 target enrollmentJanuary 2010

ConditionsCoronary Artery Bypass

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Coronary Artery Bypass
Sponsor: Imperial College London
Enrollment: 40
Locations: 1
Last Updated: 9 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Narrowing of the arteries that supply blood to the heart can lead to heart attacks and death. One way of treating this is to use artery and vein grafts from other parts of the body to bypass the narrowing. However, the blood flow from these grafts "competes" with flow through the natural coronary artery. This may contribute to grafts narrowing with time. This protocol aims to determine the pressure changes responsible for this effect. This could improve our understanding of why some grafts last longer than others.

Registry

clinicaltrials.gov

Start Date

January 2010

End Date

December 2019

Last Updated

9 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Imperial College London

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Patients with previous coronary artery bypass grafts undergoing coronary angiography and graft restudy

Exclusion Criteria

•Patient's with cardiac pacemakers, valvular heart disease, and chronic renal failure
•Unable to consent
•Contraindications to adenosine
•Contraindications to cardiac MRI