NCT00555191已完成2 期
Fructose Malabsorption in Northern Norway. Fructose Malabsorption and Irritable Bowel Syndrome.
University Hospital of North Norway2 个研究点 分布在 1 个国家目标入组 182 人开始时间: 2007年9月1日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 182
- 试验地点
- 2
- 主要终点
- VAS score og specific abdominal complaints.SGA score of relief related to abdominal complaints.
研究概览
简要总结
Different published studies has shown a possible co-variation between leakage of fructose to the great bowel and exacerbation of irritable bowel syndrome (IBS) symptoms.
The aim of the FINN trial is to study the role of fructose malabsorption in patients with IBS in order to evaluate different diagnostic criteria for fructose malabsorption and at the same time study the effect of diet treatment in this cohort of patients and estimate the prevalence of fructose malabsorption.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •IBS patients satisfying ROME 2 diagnostic criteria
排除标准
- •Seriously ill
- •Organic abdominal disease
- •Other functional bowel disease
结局指标
主要结局
VAS score og specific abdominal complaints.SGA score of relief related to abdominal complaints.
时间窗: 12 weeks
次要结局
- Estimate sensitivity,specificity,negative and positive predictive value using 50 gm fructose in breath test.Validate questionary for intolerance.Validate VAS in judging changes in abdominal complaint.Examine polymorphism i Glut5 transporter gene.(12 weeks)
研究者
研究点 (2)
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