Comparative Clinical Evaluation Of Varnya Mahakshaya Ksheer-Paka Nasya And Its Lepa In Vyanga (Melasma)
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- No improvement- 0%-25%
研究概览
简要总结
Melasma is a skin condition marked by dark brown patches that appear symmetrically on sun-exposed areas of the face, resulting from an excess of melanin. The reasons behind melasma, most significant cited factor is sunlight exposure, followed by childbirth, oral contraceptive pills use, endocrine issues, particularly thyroid abnormalities, cosmetics use, medication use, especially anticonvulsants and photosensitizing agents and genetic impacts. Vyanga Can be compared with Melasma, a prevalent skin condition that causes brown grey spots or bluish grey discoloration on the face, usually on the cheeks, forehead, chin and nasal bridge. In Ayurveda is classified under Kshudra Rogaand can be distinguished by the Niruja and Shyava Varna Mandals that are present on the face. Vata and Pitta are the Doshas that are involved in causing Vyanga and they are exaggerated by Krodha, AayasaandShoka. If we look at the treatment approach several therapy procedures has specified by the Acharyas like Abhyanga, Lepa,Pradeha, Shamana Nasya, Siraveda, Vamana and Virechana. Therefore, Ksheer-Paka Nasya and LepaofVarnya Mahakashayawill be used as medication in current study as they are Raktaprasadana, Pitta ShamakaandVatahara.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 50.00 Year(s)(—)
- 性别
- All
入选标准
- •Patient fulfilling the diagnostic criteria of Vyanga.
- •Patient of age between 20 years to 50 years.
- •Sex- both female and male.
- •Patient fit for Nasya Karma and Lepa.
排除标准
- •Skin diseases of face other than Melasma (Vyanga).
- •Hyperpigmentation since birth.
- •Ex- Nervous of ota.
- •Subjects with local inflammatory skin disorders such as herpes infection.
- •Known cases of allergies skin disease of face.
- •Uncontrolled diabetes mellitus and previously diagnosed life threatening and complicated systemic diseases.
- •Known case of Polycystic ovary disorder (PCOD)
- •Pregnant and lactating women.
结局指标
主要结局
No improvement- 0%-25%
时间窗: 15th, 29th, 42th day
Mild improvement- 25%-50%
时间窗: 15th, 29th, 42th day
Moderate improvement- 50%-75%
时间窗: 15th, 29th, 42th day
Marked improvement- 75%-100%
时间窗: 15th, 29th, 42th day
次要结局
- Exacrebation in sign and symptoms(42 days)
研究者
Dr Pravesh Kumar Mukeriya
Rishikul Campus Haridwar, Uttarakhand Ayurved University
