The Study on the Clinical Utility of Liquid Biopsy in Breast Cancer
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 200
- 主要终点
- the enumeration of circulating tumor biomarkers
研究概览
简要总结
Through this prospective clinical trial,the investigators will focus on the relationship between circulating tumor biomarkers (i.e. circulating tumor cells, circulating tumor DNA and other biomarkers) and the status of primary tumor to discuss its application for assessing prognosis and individualized therapeutic direction. Moreover, the relationship between the circulating tumor cell subpopulations based on epithelial-mesenchymal transition and molecular pathological classification of breast cancer will be determined, which may enable the determination of the value of its application in therapeutic decision making.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Female patients aged ≥18 years with histologically confirmed breast cancer.
- •The patients diagnosed with breast cancer for the first time, including postoperative patients within one month and the patients diagnosed with Stage IV breast cancer for the first time.
排除标准
- •The patients who has begun medication for breast cancer.
结局指标
主要结局
the enumeration of circulating tumor biomarkers
时间窗: up to 2 years
次要结局
未报告次要终点
研究者
Fei Ma
Department of Medical Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing,China
Peking Union Medical College