The Effect of Adding Vaginal Evening Primrose Oil to Misoprostol During Induction of Second-trimester Missed Miscarriage; a Randomized Controlled Trial
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 144
- 试验地点
- 1
- 主要终点
- The induction to fetal expulsion time.
研究概览
简要总结
Termination of pregnancy is an important subject that has complex and emotional controversies. The most common time of termination of pregnancy is the mid-trimester which has two-thirds of all serious abortion-related complications. There are many indications for mid trimester termination of pregnancy such as missed abortion, serious fetal abnormalities and lastly some women do not wish to continue a pregnancy and will often request termination of pregnancy
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Nullipara or previous vaginal delivery only
- •Bishop score was ≤ 5
- •Women who will accept to participate in the study
排除标准
- •Multiple gestations
- •Rupture of fetal membranes
- •Previous cesarean sections
- •Women with heavy bleeding
- •Evidence of low implanted placenta by US
- •Evidence of intra-uterine infection (either clinical or laboratory)
研究组 & 干预措施
study group
Misoprostol + Evening primrose oil group
干预措施: Misoprostol 100Mcg Tab (Drug)
study group
Misoprostol + Evening primrose oil group
干预措施: Evening Primrose Oil 1000 MG (Drug)
control group
Misoprostol only group
干预措施: Misoprostol 100Mcg Tab (Drug)
结局指标
主要结局
The induction to fetal expulsion time.
时间窗: 24 hours
Duration of delivery of fetus
次要结局
未报告次要终点
研究者
Ahmed Mohamed Abbas
Principal investigator
Assiut University