Evening Primrose Oil to Misoprostol During Induction of Second-trimester Missed Miscarriage
Phase 4
Completed
- Conditions
- Missed Abortion
- Interventions
- Drug: Misoprostol 100Mcg TabDrug: Evening Primrose Oil 1000 MG
- Registration Number
- NCT03584698
- Lead Sponsor
- Assiut University
- Brief Summary
Termination of pregnancy is an important subject that has complex and emotional controversies. The most common time of termination of pregnancy is the mid-trimester which has two-thirds of all serious abortion-related complications. There are many indications for mid trimester termination of pregnancy such as missed abortion, serious fetal abnormalities and lastly some women do not wish to continue a pregnancy and will often request termination of pregnancy
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 144
Inclusion Criteria
- Nullipara or previous vaginal delivery only
- Bishop score was ≤ 5
- Women who will accept to participate in the study
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Exclusion Criteria
- Multiple gestations
- Rupture of fetal membranes
- Previous cesarean sections
- Women with heavy bleeding
- Evidence of low implanted placenta by US
- Evidence of intra-uterine infection (either clinical or laboratory)
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description control group Misoprostol 100Mcg Tab Misoprostol only group study group Misoprostol 100Mcg Tab Misoprostol + Evening primrose oil group study group Evening Primrose Oil 1000 MG Misoprostol + Evening primrose oil group
- Primary Outcome Measures
Name Time Method The induction to fetal expulsion time. 24 hours Duration of delivery of fetus
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Assiut Faculty of Medicine
🇪🇬Assiut, Egypt