Comparative Evaluation of effects OF local Platelet-rich plasma, Ozone and Vacuum Assissted therapy in the management of Musculoskeletal soft tissue wounds: A Prospective Randomized Study

Wounds can heal by primary closure, delayed primary closures or secondary intention. Various surgical methods have been developed to obtain coverage in difficult wounds, like skin grafting, local rotation flaps, and myocutaneous or fasciocutaneous tissue transfers. Non operative modalities such as PRP, NPT, Ozone therapy, hyperbaric oxygen is used to enhance wound coverage and accelerate the timeline to definitive management. The primary objective of the present study is to assess the potential therapeutic effects of and comparison among autologous platelet rich plasma and ozone therapy in the healing of musculoskeletal traumatic wounds.

Therapies like Platelet rich plasma and ozone therapy act as effective adjuncts to accelerate wound healing and augment conversion to definitive management by grafting or flaps or complete gradual closure.