A Single-Blinded, Randomized, Split-Face Study of Efficacy and Safety Using Fractional Picosecond 1064 nm Nd:YAG Compared to Fractional 1550 nm Ytterbium/Erbium Fiber Laser in Facial Rejuvenation and Treatment of Dilated Pores in Asia
Phase 4
Recruiting
- Conditions
- dilated pores,facial aging,fine wrinkles
- Registration Number
- TCTR20171130003
- Lead Sponsor
- Division of Dermatology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
1.Age between 35 †50 year-old
2.No history of photo allergy
3.Compatible with follow-up schedule
4.Informed consent
Exclusion Criteria
1.Pregnancy or Giving lactationตั้งครรภ์ หรืà¸à¹ƒà¸«à¹‰à¸™à¸¡à¸šà¸¸à¸•à¸£
2.Previously treated with rejuvenation energy-based devices within 3 months
3.Underlying diseases of autoimmune diseases
4.Wounds or severe cystic acne on the face
5.Presence of pre-existing skin diseases on the face
6.Patients with severe underlying diseases
7.Withdraw
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement score in wrinkles, pore size and pigmentary lesions Week 12, Week 16, Week 20 Visual analogue scores, evaluated by blinded dermatologists and patients,Pores volume Week 0, Week 4, Week 8, Week 12, Week 16, Week 20 Visioscan,Transepidermal water loss Week 0, Week 4, Week 8, Week 12, Week 16, Week 20 DermaLab® Combo,Pigmentary melanin index Week 0, Week 4, Week 8, Week 12, Week 16, Week 20 Chromameter CR-200 Panasonic
- Secondary Outcome Measures
Name Time Method Adverse effects Week 0, Week 4, Week 8, Week 12, Week 16, Week 20 Evaluated from patients and attending dermatologists,Patient satisfaction Week 12, Week 16, Week 20 Patients satisfaction rating score