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Clinical Trials/NCT07451860
NCT07451860Not yet recruitingNot Applicable

The Role of the Triglyceride-Glucose Index in Determining the Risk of Chronic Total Occlusion in Coronary Artery Disease

Kırıkkale University1 site in 1 country200 target enrollmentStarted: March 15, 2026Last updated:
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Enrollment
200
Locations
1
Primary Endpoint
The primary outcome measure will be the difference in the triglyceride-glucose (TyG) index between patients with chronic total occlusion (CTO) and those without CTO, assessed from routinely obtained blood samples.

Study Overview

Brief Summary

We retrospectively analyzed 200 CAD patients undergoing coronary angiography between 2026-2027. Patients were grouped by CTO presence. Clinical and laboratory parameters were compared, and logistic regression was performed to identify independent predictors.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Cross Sectional

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Adults ≥18 years of age, patients undergoing coronary angiography, non-obese individuals

Exclusion Criteria

  • Patients <18 years of age, history of atrial fibrillation, pacemaker implantation, asthma, pulmonary hypertension, pregnancy, anemia, malignancy, rheumatoid arthritis, or peripheral artery disease, obesity (BMI >30 kg/m²), inaccessible patient records

Arms & Interventions

CTO

CTO (chronic total occlusion)

Intervention: triglyceride-glucose (TyG) index was calculated from routinely obtained blood samples using the formula: Triglyceride (mg/dL) × Glucose (mg/dL) / 2. (Diagnostic Test)

Non CTO

CTO (chronic total occlusion)

Intervention: triglyceride-glucose (TyG) index was calculated from routinely obtained blood samples using the formula: Triglyceride (mg/dL) × Glucose (mg/dL) / 2. (Diagnostic Test)

Outcomes

Primary Outcomes

The primary outcome measure will be the difference in the triglyceride-glucose (TyG) index between patients with chronic total occlusion (CTO) and those without CTO, assessed from routinely obtained blood samples.

Time Frame: 1 Year

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Kırıkkale University
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Rukiye Gonen Ozdemir

M.D

Kırıkkale University

Study Sites (1)

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