Effect of nano hydroxyapatite toothpaste and mouthwash on enamel and dentin erosio

Phase 3

• Conditions: enamel and dentin erosion.; Erosion of teeth; K03.2

• Registration Number: IRCT20110823007402N9
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

1) Being at least 18 years old 2) Having good general and oral health 3) Not being allergic to certain substances including oral hygiene products or dental materials 4) Non-stimulated and stimulated saliva flow more than 0.25 ml/min and more than 0.25 ml/min, respectively. 5) The absence of active caries lesions or non-carious lesions such as cervical lesions and periodontal disease 6) The absence of dental prostheses and orthodontic appliances 7) The absence of erosive lesions in the teeth 8) The possibility of visiting at recalls.

Exclusion Criteria

1) Pregnancy or intention to become pregnant during the study 2) Breastfeeding 3) Simultaneous participation in another study 4) Professional use of fluoride in the last two months 5) Inability to implement the study protocols 6) Receiving medical treatment 7) Using drugs that Interference with the flow of saliva 8) Having digestive problems 9) Smoking

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Surface microhardness, roughness and surface wear. Timepoint: 5 days after the erosive/abrasive challenge. Method of measurement: Measuring surface wear with contact profilometry, surface hardness using Vickers test, surface roughness with atomic force microscope.