AN OPEN RANDOMISED CLINICAL CONTROL TRIAL OF EFFECT OF APAMARGA KSHAR TAILA WITH ADJUVANT DRUG THERAPY IN MANAGEMENT OF SHARAVIKA PRAMEHA PIDIKA WITH SPECIAL REFERENCE TO DIABETIC ULCER

Diabetes is a disease known for its multifaceted complications. Diabetic ulcer is one of the major complications of diabetes. Thousands of researches are being carried out on this in which Ayurveda has a major role. Brihatatryis have described Prameha Pidaka as a major complication of Prameha. These Pidakas are mainly found in muscular region, joints and vital points (Marmas). Different numbers of Prameha Pidakas are mentioned in Ayurvedic Classics. According to Sushruta there are 10 different types of Prameha Pidakas.Prameha pidika is seen as debilitating and Scoring disorder seen in the human being suffering from diabetes.it is very important and widely described chapter of shalya tantra.Su.Ni. 6/14

Pidaka which is raised at the margin and dipped in its centre, so as to resemble as Saucer in its shape is called as Sharavika. 

Diabetese affects more than 9.3% of Indian adult population. Up to 25% of diabetic patients develop foot ulcers. More than half of foot ulcers become infected and require hospitalisation and 20% of infections results in amputation. Early effective management can reduce the severity of complications such as preventable amputations and possible mortality and can also improve overall quality of life.

This study is randomized open controlled trial to evaluate the efficacy of Apamarga Kshar taila in the management of Sharavika Prameha PIdika as trial drug and EUSOL as control drug. Trial and control drugs applied on the diagnosed cases of Sharavika prameha pidika for 15 days and as per need. After 15 days patient is advice to come on 5th, 10th, 15 th day for follow up. 44 patients in each group will be studied. Study will be conducted in India. Outcome of study will be asses onbetter healing and reduction of signs and symptoms of wound.