To assess the efficacy of addition of intravenous levosulpirideto dexamethasone as prophylaxis for PONV in patientsundergoing B/L TKR: a prospective, randomized, doubleblinded, controlled study".

Total knee Arthroplasty remains one of the most commonly performed major orthopedic procedures. The number of procedures in most countries has increased rapidly over the past decade. The incidence of postoperative nausea and vomiting in patients undergoing Arthroplasty is high if not given any antiemetics. We will assess the efficacy of addition of intravenous levosulpiride to dexamethasone as prophylaxis for post operative nausea vomiting in patients undergoing Bilateral total knee replacement in a prospective, randomized, double blind manner. We will be having 100 patients with 50 in each group both male and female patients and excluding patients with history of anaphylaxis or allergy to the study drugs and patients refusing for consent etc.