Prevalence and Impact of Hospital Malnutrition on Associated Outcomes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 2,126
- 试验地点
- 1
- 主要终点
- Change in prevalence of risk for malnutrition during the period of hospitalization
研究概览
简要总结
Malnutrition of patients on admission to hospitals are estimated to be as high as 60%, although the prevalence varies between countries. The impact of malnutrition on patient recovery and discharge is severe, with extensive cost implications. This study aims to assess the prevalence of at risk for malnutrition among adult patients admitted to hospital across 3 countries on the African continent.
详细描述
The prevalence of malnutrition on admission to hospital varies between 15-60%. Knowing the extent of the problem and identifying at-risk patients should be a priority task since malnutrition is associated with increased hospital-related complications; longer length of stay, increased costs related to treatment and higher mortality. Post discharge, malnourished patients have also been linked to more frequent re-admissions, higher morbidity and mortality. Various screening tools are available, including the Nutrition Risk Screening-2002 recommended by European Society for Clinical Nutrition and Metabolism as the preferred screening tool for malnutrition in hospitals in Europe. ASPEN recommends a more comprehensive evaluation and diagnosis procedure. In South Africa, and the rest of Africa, nutritional screening is not routinely done and the investigators do not have any reliable national statistics indicating the extent of the problem. The aim of this study is to determine the prevalence of malnutrition on admission to hospital and to identify the impact thereof on relevant outcomes. Two different internationally recognised tools will be used and validated for the African context. In this multi-country, multi-centre descriptive cross-sectional study 3 hospitals in South Africa, 1 in Ghana and 2 in Kenya will be included. Adult patients (n=400 per hospital) will be screened on admission and at discharge and relevant outcomes (in-hospital and 3-month post-discharge) will be charted. A 50% sub-sample will be used to validate the 2 instruments.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients older than 18 years of age
- •Males and females
- •Admitted to hospital within the past 48 hours
- •Conscious
- •Informed consent provided
排除标准
- •Paediatric patients younger than 18 years
- •Pregnant and lactating females
- •Patients admitted to ICU, burns or relevant acute care wards
- •Patients admitted to psychiatry or eating disorders units
- •Patients on dialysis
结局指标
主要结局
Change in prevalence of risk for malnutrition during the period of hospitalization
时间窗: Baseline; day 28
Baseline (Admission) data will be gathered during to the first 48 hours after hospital admission. Discharge data (Day 28) is collected on day of actual discharge or on day 28 of hospitalization if patient is staying in hospital longer than that. A NRS-2002 score greater than 3 indicates risk for malnutrition.
次要结局
- Number of patients obtaining similar screening scores as a measure of relative validity of the different screening tools used against each other(Baseline and day 28)
- Association between risk for malnutrition and in-hospital and post-discharge nutritional / medical indicators(Baseline; day 28 and Day 90)
研究者
Prof Renee Blaauw
Professor
University of Stellenbosch