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Clinical Trials/NCT02508974
NCT02508974
Completed
Not Applicable

Prevalence and Impact of Hospital Malnutrition on Associated Outcomes

University of Stellenbosch1 site in 1 country2,126 target enrollmentJanuary 2015
ConditionsMalnutrition

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Malnutrition
Sponsor
University of Stellenbosch
Enrollment
2126
Locations
1
Primary Endpoint
Change in prevalence of risk for malnutrition during the period of hospitalization
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

Malnutrition of patients on admission to hospitals are estimated to be as high as 60%, although the prevalence varies between countries. The impact of malnutrition on patient recovery and discharge is severe, with extensive cost implications. This study aims to assess the prevalence of at risk for malnutrition among adult patients admitted to hospital across 3 countries on the African continent.

Detailed Description

The prevalence of malnutrition on admission to hospital varies between 15-60%. Knowing the extent of the problem and identifying at-risk patients should be a priority task since malnutrition is associated with increased hospital-related complications; longer length of stay, increased costs related to treatment and higher mortality. Post discharge, malnourished patients have also been linked to more frequent re-admissions, higher morbidity and mortality. Various screening tools are available, including the Nutrition Risk Screening-2002 recommended by European Society for Clinical Nutrition and Metabolism as the preferred screening tool for malnutrition in hospitals in Europe. ASPEN recommends a more comprehensive evaluation and diagnosis procedure. In South Africa, and the rest of Africa, nutritional screening is not routinely done and the investigators do not have any reliable national statistics indicating the extent of the problem. The aim of this study is to determine the prevalence of malnutrition on admission to hospital and to identify the impact thereof on relevant outcomes. Two different internationally recognised tools will be used and validated for the African context. In this multi-country, multi-centre descriptive cross-sectional study 3 hospitals in South Africa, 1 in Ghana and 2 in Kenya will be included. Adult patients (n=400 per hospital) will be screened on admission and at discharge and relevant outcomes (in-hospital and 3-month post-discharge) will be charted. A 50% sub-sample will be used to validate the 2 instruments.

Registry
clinicaltrials.gov
Start Date
January 2015
End Date
December 2017
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Prof Renee Blaauw

Professor

University of Stellenbosch

Eligibility Criteria

Inclusion Criteria

  • All patients older than 18 years of age
  • Males and females
  • Admitted to hospital within the past 48 hours
  • Conscious
  • Informed consent provided

Exclusion Criteria

  • Paediatric patients younger than 18 years
  • Pregnant and lactating females
  • Patients admitted to ICU, burns or relevant acute care wards
  • Patients admitted to psychiatry or eating disorders units
  • Patients on dialysis

Outcomes

Primary Outcomes

Change in prevalence of risk for malnutrition during the period of hospitalization

Time Frame: Baseline; day 28

Baseline (Admission) data will be gathered during to the first 48 hours after hospital admission. Discharge data (Day 28) is collected on day of actual discharge or on day 28 of hospitalization if patient is staying in hospital longer than that. A NRS-2002 score greater than 3 indicates risk for malnutrition.

Secondary Outcomes

  • Number of patients obtaining similar screening scores as a measure of relative validity of the different screening tools used against each other(Baseline and day 28)
  • Association between risk for malnutrition and in-hospital and post-discharge nutritional / medical indicators(Baseline; day 28 and Day 90)

Study Sites (1)

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