Incidence, risk factors and outcomes of early post-operative stroke in a university-based, tertiary care hospital: A 7-year retrospective case-control study

Completed

• Conditions: Operation; Stroke; Risk factors; Incidence; Postoperative stroke; Anesthesia

• Registration Number: TCTR20220317006
• Lead Sponsor: Department of Anesthesiology, Faculty of Medicine Siriraj Hospital

Brief Summary

The incidence of early post-operative stroke was 0.015%. ASA physical status 3 or higher (OR 3.12), operation time longer than 120 min (OR 10.69), and intra-operative hypotension and inotrope/vasopressor use (OR: 2.80) were risk factors. Compared to the controls, stroke patients had higher rates of planned and unplanned ICU admission, length of stay, ventilator use, and death. Despite low incidence, stroke is associated with poor clinical outcomes and increased mortality.

Detailed Description

Not available

Study Timeline

• Study Completion: 2021-12-31
• Study Start: 2022-03-17
• Results First Posted: 2023-07-14
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 172

Inclusion Criteria

1. The patients age 18 yeras old or older scheduled for operation during Jan 2015-Dec 2021.
2. The patients whose anesthesia and medical records were in complete forms and registered in the Department of Anesthesiology and Siriraj Hospital database

Exclusion Criteria

1. The patients who did not undergo operation according to any reason e.g. cancellation of operation, change of treatment plan, etc.
2. The patients whose anesthesia and/or medical records are uncompleted.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postoperative stroke 24-48 hours number of stroke events recorded in medical charts

Secondary Outcome Measures

Name	Time	Method
length of hospital stay anytime recorded in the medical reports days