Physical Activity Levels in COVID-19 Patients Admitted to Intensive Care

Completed

• Conditions: Critical Illness; ICU Acquired Weakness; COVID-19; Ards
• Interventions: Other: Physiotherapy

• Registration Number: NCT04396197
• Lead Sponsor: University Hospital Birmingham NHS Foundation Trust

Brief Summary

This is an observational study exploring the levels of mobility and rehabilitation in patients admitted to critical care with a confirmed diagnosis of COVID-19

Detailed Description

An admission to an intensive care unit (ICU) often results in significant muscle weakness and physical deconditioning, which can take many months or even years for recovery. Early and progressive programmes of rehabilitation are recommended to limit any muscle loss and support recovery as early as possible. Patients admitted to intensive care with COVID-19 have been found to require prolonged periods of mechanical ventilation, high sedation and neuromuscular blocking use and as a result require prolonged stays in the ICU. As yet no data exists to examine the specific physical impact this may have, or whether it is safe and feasible to commence this earlier rehabilitation within the ICU for patients with a diagnosis of COVID-19. Our study set out to evaluate the levels of rehabilitation which were delivered in a large acute NHS trust.

Study Timeline

• Study Start: 2020-03-01
• Status Verified: 2020-05
• Primary Completion: 2020-05-08
• Study Completion: 2020-05-08
• Study First Submitted: 2020-05-17
• Study First Submitted QC: 2020-05-19
• Last Update Submitted: 2020-05-19
• Study First Posted: 2020-05-20
• Last Update Posted: 2020-05-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 92

Inclusion Criteria

• having a confirmed diagnosis of COVID-19
• being mechanically ventilated for at least 24 hours
• surviving to critical care discharge.

Exclusion Criteria

• none

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
COVID-19	Physiotherapy	Observations taken of standard physiotherapy practice. All patients are assessed daily and receive respiratory care and rehabilitation as deemed appropriate by the treating therapist

Primary Outcome Measures

Name	Time	Method
Mobility level	At ICU discharge, an average of 3 weeks	Highest level of mobility achieved at the point of ICU discharge
Time taken to first mobilise	during ICU admission, up to 3 weeks	Time taken to first mobilise, defined as sitting on the edge of the bed or higher

Secondary Outcome Measures

Name	Time	Method
Discharge location	Hospital discharge, up to 2 months	Discharged to home, home with rehab, or a community rehab facility

Trial Locations

Locations (1)

UHB NHS Foundation Trust; 🇬🇧 Birmingham, United Kingdom