Effect of vaginal PH on efficacy of controlled- release Dinoprostone vaginal insert for cervical ripening/ labor induction.

Phase 2

• Conditions: abor Induction.; Pregnancy, childbirth and the puerperium; O00-O99

• Registration Number: IRCT138904091760N7
• Lead Sponsor: Vice Chancellor for Research and Technology, Babol University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 147

Inclusion Criteria

women with age 16-35 years, nulligravida, single tone pregnancy, cephalic presentation, Bishop Score equal or less than 5, no contraindication for vaginal delivery, uterine contractions did not start. Exclusion criteria: known allergy to prostaglandins, membrane rupture, fetal infection, history of previous surgery on the uterus and the previous induction of labor in recent pregnancy.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cervix softening. Timepoint: After 12 hours of placing a vaginal suppository. Method of measurement: Bishop score.

Secondary Outcome Measures

Name	Time	Method
Duration of the stages of labor. Timepoint: Intervals between each stage (Latent phase, the active phase and second stage of labor). Method of measurement: From time to start feeling regular contractions to dilatation 3-5 cm (Latent phase) / Dilatation from 3-5 cm to complete dilatation (active phase) / Since the complete withdrawal dilatation to fetus (Second stage of labor).