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临床试验/DRKS00028653
DRKS00028653已完成不适用

Correlation Between the Risk of Peri-Implantitis and Increased Levels of Proinflammatory Cytokines following an interaction between Titanium dioxide and Macrophages

Mund-, Kiefer-, Gesichschirurgie (MKG) Universitätsklinik Hamburg-Eppendorf0 个研究点目标入组 60 人开始时间: 2022年4月12日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
60

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 Years 至 one(—)
性别
All

入选标准

  • 20 patients without titanium implants in the jawbone
  • - 20 patients with at least one titanium implant in the jawbone without peri-implantitis
  • - 20 patients with at least one titanium implant in the jawbone with peri-implantitis or implant loss

排除标准

  • Patients with titanium implants outside the jawbone and risk or high risk factors according to ITI-consensus-conference:
  • Risk factors:
  • - Radiated bone
  • - Inadequately controlled Diabetes mellitus (HbA1c > 7,5%)
  • - Hemorrhagic diathesis
  • - Antiresorptive therapies (bisphosphonates, denosumab)
  • - Poor oral hygiene (from grad 3 according to
  • Sillness and Löe)
  • High-risk factors
  • - Serious systemic diseases (e.g. leukemia, TBC)
  • - Immunocompromised patients (e.g. HIV)
  • - Drug abuse
  • - Mental altered patients
  • - Uncooperative patients

研究者

发起方
Mund-, Kiefer-, Gesichschirurgie (MKG) Universitätsklinik Hamburg-Eppendorf

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