A randomized controlled trial of timing for tissue resection in Chronic limb-threatening ischemia after revascularizatio

Phase 3

• Conditions: Chronic limb-threatening ischemiaCritical limb ischemiaGangreneDebridementTissue resectiontiming; CLTI; CLI; Debridement; tissue resection; timing

• Registration Number: TCTR20220810007
• Lead Sponsor: Faculty of Medicine Ramathibodi Hospital, Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-08-10
• Last Update Posted: 19 August 2024
• Study Completion: 2025-01-31

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 146

Inclusion Criteria

1. Diagnosed Chronic limb-threatening ischemia
2. Successful revascularization
3. Accept informed consent

Exclusion Criteria

1. Moderate wound infection before allocation
2. Systemic inflammatory response syndrome before allocation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Wound healing time at the date of wound healed time after tissue resection to the date of wound completely healed

Secondary Outcome Measures

Name	Time	Method
Wound infection rate assess every follow-up visit until the wound healed Wound characteristic,Major adverse limbs event Until date of wound healed reoperation (revascularization/tissue resection), Major amputation,Major Adverse Cardiovascular Events Until date of wound healed Myocardial infarction, Stroke, Death,Length of hospital stay until discharge from first tissue resection operation Cumulative hospitalized days