Intramuscular Concentrations of Glucose, Lactate, Glutamate, and Glycerol Comparing Chronic Exercise Induced Compartment Syndrome Patients to Controls Before and Following Exercise

Not Applicable

• Conditions: Healthy volunteers; T79.62

• Registration Number: DRKS00021589
• Lead Sponsor: Bundesinistut für Sportwissenschaft (BISp)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2011-08-12
• Study Start: 2020-04-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Patients:
• age > 15 und < 50 years
• intensive sport/running activity
• symptoms at one or two legs
• anterior or deep posterior chronic exercise induced compartment syndrome
• no previous injury/operation of the lower extremities
• typical symptoms more than 12 weeks (spontaneous onset, reproducibly activated by running, increasing pain stops activity, pain over the involved compartment relieved by rest)

Asymptomatic group (Control group):
• age >15 and <50 years
• sport activity level comparable to the patients
• anthropometrics comparable to the patients
• no previous injury/operation of the lower extremities
• no chronic compartment syndrome of the leg

Exclusion Criteria

• systemic diseases
• acute or trauma induced onset of symptoms
• duration of the complaints <12 weeks
• abnormal orthopaedic lower extremity findings (malpositions, joint injuries, hypermobility)
• acute and degenerative lumbar spine diseases
• uncertain compliance
• peripheral artery diseases
• venous insufficiency
• lower leg stress injury
• nerve compression
• muscular diseases or muscle injuries

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Concentration of lactate, glucose, glutamate, and glycerol pre- and post-exercise.