Cerebral Oximetry With Near-infrared Spectroscopy and Negative Postoperative Behavioral Changes in Pediatric Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cognitive Dysfunction
- Sponsor
- Hospital Clínico Universitario de Valladolid
- Enrollment
- 198
- Primary Endpoint
- Incidence of Negative Postoperative Behavioral Changes
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
The main objective of the present study was to evaluate whether cerebral oxygen saturation is associated with an increase of NPOBC in pediatric patients undergoing major surgery.
Detailed Description
This prospective and observational study involved consecutive patients aged between 2 and 12 years undergoing a major surgery using general anesthesia. Cerebral oxygen saturation, non-invasive arterial pressure, pulse oximetry, and heart rate were recorded at the following stages of the surgical intervention: baseline, induction, intubation, surgical incision, end of surgery, and extubation. Preoperative anxiety was evaluated by using the modified Yale Preoperative Anxiety Scale, and NPOBC was determined by using the Post-Hospital Behaviour Questionnaire on 7th and 28th postoperative days. A logistic regression was created to identify factors associated with the development of NPOBC
Investigators
Estefanía Gomez Pesquera
MD Anesthesiologist
Hospital Clínico Universitario de Valladolid
Eligibility Criteria
Inclusion Criteria
- •Patients aged between 2 and 12 years undergoing major surgery using general anesthesia.
Exclusion Criteria
- •Children aged below 2 or over
- •Neuropsychiatric disorder, or undergoing an emergency surgery.
Outcomes
Primary Outcomes
Incidence of Negative Postoperative Behavioral Changes
Time Frame: on 7th and 28th postoperative days
NPOBC was measured by using thePost-Hospital Behaviour Questionnaire.
Secondary Outcomes
- Number of children with cerebral desaturation and NPOBC(on 7th and 28th postoperative days)