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临床试验/NCT07683078
NCT07683078已完成不适用

Effect of Adding Vastus Medialis Nerve Block to Adductor Canal Block on Postoperative Analgesia Following Anterior Cruciate Ligament Reconstruction: A Prospective Randomized Controlled Trial

Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization1 个研究点 分布在 1 个国家目标入组 104 人开始时间: 2026年3月14日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
104
试验地点
1
主要终点
Postoperative Pain Intensity

研究概览

简要总结

Anterior cruciate ligament (ACL) reconstruction is frequently associated with moderate to severe postoperative pain, which can delay mobilization and rehabilitation. The adductor canal block (ACB) is widely used for postoperative pain management because it provides effective analgesia while preserving quadriceps muscle strength. However, pain originating from the medial aspect of the knee may not be adequately controlled with ACB alone because the nerve to the vastus medialis may not be consistently anesthetized.

This prospective randomized controlled trial evaluates whether adding a vastus medialis nerve block (VMNB) to a standard adductor canal block improves postoperative pain control in patients undergoing elective arthroscopic ACL reconstruction. Participants are randomly assigned to receive either ACB alone or ACB combined with VMNB before surgery, while all patients receive the same standardized general anesthesia, surgical technique, and postoperative analgesic regimen.

The primary outcome is postoperative pain intensity measured using the Visual Analog Scale (VAS) at 1, 6, 12, and 24 hours after surgery. Secondary outcomes include postoperative opioid consumption, time to first mobilization, length of hospital stay, and block-related complications. The results of this study may help determine whether the addition of a vastus medialis nerve block provides clinically meaningful benefits and may contribute to improving postoperative pain management following ACL reconstruction.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Supportive Care
盲法
Triple (Participant, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adults aged 18 to 65 years.
  • Scheduled for elective primary arthroscopic anterior cruciate ligament (ACL) reconstruction.
  • American Society of Anesthesiologists (ASA) physical status I or II.
  • Ability to provide written informed consent.

排除标准

  • Previous surgery on the ipsilateral knee.
  • Bilateral knee surgery.
  • Coagulopathy or ongoing anticoagulant therapy contraindicating regional anesthesia.
  • Peripheral neuropathy or neuromuscular disease.
  • Local infection at the block injection site.
  • Known allergy or hypersensitivity to amide local anesthetics.
  • Contraindication to regional anesthesia.
  • Refusal to participate in the study.

研究组 & 干预措施

Adductor Canal Block

Active Comparator

Participants received an ultrasound-guided adductor canal block before elective arthroscopic anterior cruciate ligament reconstruction. All participants received standardized general anesthesia and postoperative analgesic management.

干预措施: Adductor Canal Block (ACB) Only (Procedure)

Adductor Canal Block Plus Vastus Medialis Nerve Block

Active Comparator

Participants received an ultrasound-guided adductor canal block combined with an ultrasound-guided vastus medialis nerve block before elective arthroscopic anterior cruciate ligament reconstruction. All participants received standardized general anesthesia and postoperative analgesic management.

干预措施: Adductor Canal Block (ACB) Only (Procedure)

Adductor Canal Block Plus Vastus Medialis Nerve Block

Active Comparator

Participants received an ultrasound-guided adductor canal block combined with an ultrasound-guided vastus medialis nerve block before elective arthroscopic anterior cruciate ligament reconstruction. All participants received standardized general anesthesia and postoperative analgesic management.

干预措施: Vastus Medialis Nerve Block (Procedure)

结局指标

主要结局

Postoperative Pain Intensity

时间窗: 24 hours after surgery

Postoperative pain intensity will be assessed using the 10-cm Visual Analog Scale (VAS) at rest at 1, 6, 12, and 24 hours after surgery. VAS scores range from 0 (no pain) to 10 (worst imaginable pain).

次要结局

  • Postoperative Opioid Consumption(24 hours after surgery)
  • Time to First Mobilization(24 hours after surgery)
  • Length of Hospital Stay(24 hours after surgery)

研究者

发起方
Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
申办方类型
Other
责任方
Principal Investigator
主要研究者

Rasim Onur Karaoglu

Medical Doctor

Bagcilar Training and Research Hospital

研究点 (1)

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