Predictors of Postoperative Pain

Not Applicable

Completed

• Conditions: Postoperative Pain
• Interventions: Device: Thermal Sensory Analyzer (Senselab)

• Registration Number: NCT01449318
• Lead Sponsor: American University of Beirut Medical Center

Brief Summary

The purpose of the study is to prove that pain scores generated from painful stimuli applied preoperatively may help identify the inter-individual variability in pain perception.

Detailed Description

Psychological factors and experimental pain models such as as electrical, pressure, heat, or cold stimuli have been identified as predictors of pain intensity and opioid consumption postoperatively. This study will investigate, in addition to the factors described above, the ability of pain scores generated from painful stimuli postoperatively in predicting postoperative pain.

Study Timeline

• Study First Submitted: 2011-09-28
• Study First Submitted QC: 2011-10-07
• Study First Posted: 2011-10-10
• Study Start: 2012-07
• Status Verified: 2013-09
• Primary Completion: 2014-03
• Study Completion: 2014-03
• Last Update Submitted: 2014-05-15
• Last Update Posted: 2014-05-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

• Patients undergoing abdominal hysterectomy through a pfannenstiel incision
• American Society of Anesthesiologists (ASA)Class I-III

Exclusion Criteria

• Patients with a history of psychiatric disease
• Diabetic or alcoholic patients who may have impaired sensation due peripheral neuropathies
• chronic opioid or nonsteroidal antiinflammatory drug use
• chronic pain conditions

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Patients undergoing hysterectomy	Thermal Sensory Analyzer (Senselab)	-

Primary Outcome Measures

Name	Time	Method
pain scores from IV insertion	15 minutes prior to induction

Secondary Outcome Measures

Name	Time	Method
Pain from thermal stimuli	24 to 48 hours before surgery	Pain from thermal stimuli will be measure at two sites: site of surgery and at the forearm.
Suprathreshold Thermal pain intensity	24 to 48 hours before surgery	Suprathreshold Thermal pain intensity will be recorded at two site: site of surgery and forearm
postoperative pain	within 1-2 hours after arrival to recovery room; and at 12 hours, 24 hours, 36 hours and 48 hours after surgery	Postoperative pain will be measured upon arrival to the Post Anesthesia Care Unit (PACU)before morphine consumption and after morphine consumption, at rest and at movement.
Anxiety	24 to 48 hours before surgery
suprathreshold thermal unpleasantness intensity	24 to 48 hours before surgery
Expectation about pain	24 to 48 hours before surgery
Morphine consumption	within 1-2 hours after arrival to recovery room; and at 12 hours, 24 hours, 36 hours and 48 hours after surgery

Trial Locations

Locations (2)

American Unversity of Beirut Medical Center; 🇱🇧 Beirut, Lebanon

AUBMC; 🇱🇧 Beirut, Lebanon