Open Label Study of Duloxetine for the Treatment of Phantom Limb Pain

Not Applicable

Terminated

• Conditions: Chronic Phantom Limb Pain

• Registration Number: NCT00425230
• Lead Sponsor: Baylor College of Medicine

Brief Summary

This is a study to assess the possible benefit of duloxetine in the treatment of chronic phantom limb pain.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-01
• Study First Submitted: 2007-01-19
• Study First Submitted QC: 2007-01-19
• Study First Posted: 2007-01-22
• Study Completion: 2007-06
• Status Verified: 2022-08
• Last Update Submitted: 2022-08-10
• Last Update Posted: 2022-08-12

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

1. Chronic PLP > 6 months
2. Short-Form McGill Pain Questionnaire Sensory Pain Rating Index raw score ≥ 16
3. Age ≥ 18 years old
4. Inpatient or Outpatient
5. Able to come to all appointments, in the opinion of the investigator
6. Able to give informed consent, in opinion of investigator

Exclusion Criteria

1. Current Major Depressive disorder, Anxiety Disorder, or Psychotic disorder assessed by the Mini International Neuropsychiatric Interview (MINI)
2. Substance abuse or dependence within the last six months, as assessed by the MINI
3. Known Diabetes Mellitus to exclude diabetic peripheral neuropathy
4. History of coronary artery disease, hepatic disease, renal disease
5. Other pain syndromes
6. Any unstable medical conditions in the opinion of the investigator
7. Other psychotropic medications excluding hypnotics

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
McGill Short Form Pain Questionairre

Secondary Outcome Measures

Name	Time	Method
Fiser Side effect scale
visual analog pain scale
Present Pain intensity
Tylenol # 3 consumption

Trial Locations

Locations (1)

Micheal E. DeBakey Veterans Hospital; 🇺🇸 Houston, Texas, United States