Spinal Cord Injury: Endurance, Strength and Cardiac Function Induced by Efficient Training Protocols

Not Applicable

Completed

• Conditions: Cardiovascular Disease
• Interventions: Device: Ergometry

• Registration Number: NCT00987155
• Lead Sponsor: Norwegian University of Science and Technology

Brief Summary

1. Measurements of peak oxygen uptake (VO2peak) during passive leg cycling (PLC) combined with arm crank ergometry (ACE), leg vascular occlusion (100mmHg above systolic BP) combined with ACE, and FES isometric contractions combined with ACE in spinal cord injured (SCI). All the above mentioned parameters will be compared to Functional Electrical Stimulated (FES) lower extremity cycling combined with ACE (FEShybrid). The hypothesis is that VO2peak is significantly higher during FES hybrid cycling when compared to peak and submaximal PLC, leg vascular occlusion and ACE. But the values for VO2peak during FES isometric contractions combined with ACE is not significantly different from FES hybrid cycling.

2. Comparison of sub-maximal and peak VO2 values during arm crank (ACE) and wheelchair ergometry (WCE) in persons with spinal cord injury. The hypothesis is that wheelchair propulsion due to higher energy expenditure show higher work output and VO2peak than ACE.

3. Does 6 weeks of maximal strength training improve SCI subjects performance during WCE? WCE after 6 weeks maximal strength training is less strenuous owing to better work economy/ efficiency.

4. Effect from aerobic high intensity hybrid training on stroke volume (SV) and VO2peak in spinal cord injured men.

8 weeks of high intensity 4 times 4 interval training at 85-90% of peak heart rate during hybrid cycling. Hypothesis; VO2peak and SV will be significantly increased from training.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-01
• Study First Submitted: 2009-09-28
• Study First Submitted QC: 2009-09-29
• Study First Posted: 2009-09-30
• Primary Completion: 2012-02
• Study Completion: 2012-05
• Status Verified: 2017-01
• Last Update Submitted: 2017-01-16
• Last Update Posted: 2017-01-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• Paraplegia, sensorimotor complete injury AIS A to motor complete, sensory incomplete AIS B. Chronic neurological state with stabile spontaneous recovery compared to baseline AIS. At least year since injury.
• Be able to tolerate direct current stimulation in the means of FES
• Living in Health region IV and V, Norway.

Exclusion Criteria

• Pacemaker (demand type)
• Known cancer
• Known pregnancy
• Severe autonomic dysreflexia
• Gross contractures

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
high intensity interval training	Ergometry	8 weeks of high intensity 4 times 4 interval training at 85-90% of peak heart rate during hybrid cycling

Primary Outcome Measures

Name	Time	Method
Maximal oxygen uptake	2 years

Secondary Outcome Measures

Name	Time	Method
Blood lactate	2 years
Perceived Exertion	2 years
Blood Pressure	2 years
Generated power (W)	2 years

Trial Locations

Locations (1)

St Olav University Hospital; 🇳🇴 Trondheim, Norway