Efficacy of Ketoprofen Before Intrauterine Device Insertion
- Registration Number
- NCT02905058
- Lead Sponsor
- Assiut University
- Brief Summary
IUD can cause pain and discomfort in several ways: Use of the tenaculum to grasp the cervix and straighten the uterus for proper insertion; trans-cervical actions including measuring uterine depth, inserting the IUD insertion tube, and removing the tube; and placement of the device in the uterus.
- Detailed Description
To minimize the discomfort and the hazards of an IUD insertion, several measures have been proposed including NSAIDs, anxiolytics, and local anesthetics in the form of intracervical gel, cervical and para-cervical block, but there have not done enough studies about their effectiveness. According to the review published in the Cochrane, non-steroidal anti-inflammatory drugs and misoprostol are not effective on reducing an IUD insertion pain.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 100
- Women not taken analgesics or anxiolytics in the 24 hours prior insertion
- Women not taken misoprostol prior to insertion
- No contraindication to Non-steroidal drugs
- Women who will accept to participate in the study
- Any contraindication to device placement
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Ketoprofen Ketoprofen women will take one tablet 150 mg one hour before the procedure Placebo placebo women will take one placebo tablet one hour before the procedure
- Primary Outcome Measures
Name Time Method Mean pain score during IUD insertion 5 minutes
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Ahmed Abbas
🇪🇬Assiut, Cairo, Egypt