Bispectral Index as an Analgesia Monitoring in Severely Ill Patient: Effect of Remifentanyl
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- BIS variation during bronchoalveolar lavage
研究概览
简要总结
The aim of this protocol is to study the prophylactic effect of remifentanil on bispectral index variation during a nociceptive stimuli.
详细描述
Pain is difficult to estimate in ICU because most of the patients are sedated. Bispectral index could be helpful in detecting this pain in ICU patients. Remifentanil is a morphinomimetic product with short half life that could be interesting for short nociceptive stimuli, as bronchoalveolar lavage.
The purpose of this study is to evaluate the impact of remifentanil infusion on bispectral index (BIS) variations during bronchoalveolar lavage.
It is a prospective, double blind study, versus placebo on 40 sedated and critically ill patients.
The hypothesis is that BIS can study analgesia in sedated patient.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Sedated patient with mechanical ventilation with suspected nosocomial pneumonia
排除标准
- •Pace maker
- •Neurologic illness
- •Hemodynamic instability
- •Hypothermia
结局指标
主要结局
BIS variation during bronchoalveolar lavage
次要结局
- Systolic blood pressure, diastolic blood pressure, heart rate viation