Effects Of Walnut-Enriched Diet On Blood Lipids And Glucose Profiles In Hyperlipidemic Subjects: A Randomized-Controlled Trial: A Randomized-Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 37
- 主要终点
- Reduction in serum lipids and fasting glucose levels
研究概览
简要总结
Walnuts have been shown to reduce serum lipids in hyperlipidemic individuals with a well-controlled feeding trials. Current study have been determined the effects of daily walnut consumption on serum lipids, fasting glucose and insulin levels in hyperlipidemic individuals.
详细描述
In this, randomized controlled trial, mild to moderate hyperlipidemic subjects were randomly divided into 2 groups as walnut-enriched (n=20) and control (n=17) groups for 6 weeks. All subjects adhered to a medical nutrition therapy as low-fat and low-cholesterol diet. The walnut-enriched group was supplemented with 40 g/day of walnuts added to their diets. In order to follow nutritional status of subjects, they were visited every 15 days (in total 4 times). Anthropometric measurements of the subjects were taken and were monitored at each visit during the study. Blood samples were measured at the beginning and again at the end of the study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 30 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Hyperlipidemic patients who are not using any lipid lowering medications
- •Non-smoker
- •No alcohol consumption
- •Individuals who are having ≤30kg/m2
- •Individuals who do not have any allergy for nut consumption
- •Female participants who are not pregnant or breastfeeding
- •Individuals should not be in a weight loss programme
- •Having not consumed regular nuts for the last 1 month,
- •Except hypertension, they should not have other chronic diseases (such as diabetes, chronic renal failure)
- •No intense exercise
排除标准
- •Failure to meet the criteria for inclusion criteria.
研究组 & 干预措施
Control Group
In 'Control group' participants had 6 week follow-up without any intervention.
Interventional Group
In 'Interventional group' participants had 6 week follow-up and during that period of time, they were asked to consume 40g/day walnut. Participants in intervention group was ensured to consume all 40g of walnut every day, during their snack times for 6 weeks.
干预措施: Walnut-enriched Group (Dietary Supplement)
结局指标
主要结局
Reduction in serum lipids and fasting glucose levels
时间窗: Six weeks
In both group, participants have decreased serum total cholesterol and LDL-cholesterol.However especially walnut-enrcihed group significantly changed fasting glucose and insulin levels.
次要结局
未报告次要终点
研究者
Gözde Okburan
Senior Instructor
Eastern Mediterranean University