Physical activity and physical fitness in children after Orthotopic Liver Transplantation aged 6 -1 2 years

Completed

Conditions: physical activity liver transplantation
10019654

Registration Number: NL-OMON40982

Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 26

Inclusion Criteria

Post OLT (more than one year)
age 6-12 years
good functioning liver (normal PT, Bilirubine, Albumine)
Being able to follow test instructions
parental consent and child assent (12 years)

Exclusion Criteria

Medical event that might intervene with the outcome of testing (other than associated with OLT) for instance recent trauma/fracture and secondary diagnosis like down syndrome.
Medical status that will not allow maximal exercise testing (e.g. acute fever, heart conditions).

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Physical activity as assessed by 7 days activity monitoring using an Actical<br /><br>accelerometer and an activity diary<br /><br>Aerobic exercise capacity (VO2 peak) as assessed during a graded exercise test<br /><br>with respiratory gas analysis</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Muscle strength as assessed with a hand-held dynamometry<br /><br>Health related quality of life and fatigue as assessed with the Paediatric<br /><br>Quality of Life Inventory (PedsQl)<br /><br>Pain (general) as assessed with the 10 centimeter Visual Analogue Scale (VAS)<br /><br>Anthropometry (weight, height, fat free mass)<br /><br>Participation as assessed by the Children*s Assessment of Participation and<br /><br>Enjoyment (CAPE)</p><br>