NCT04267094TerminatedNot Applicable
A Single-center, Multi-scanner, Observational Study to Investigate the Impact of Reduced Radiation Dose and Iterative Reconstruction Algorithms on Coronary Calcium Score in Comparison to the Standard Normal Radiation Dose -Filtered Back Projection Method
University of Pennsylvania2 sites in 1 country190 target enrollmentStarted: July 1, 2017Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Terminated
- Sponsor
- University of Pennsylvania
- Enrollment
- 190
- Locations
- 2
- Primary Endpoint
- Calcium score
Study Overview
Brief Summary
Evaluation of reduced radiation dose iterative reconstruction reconstructions for calcium scoring compared to full dose filtered back projection reconstructions
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Single Group
- Primary Purpose
- Diagnostic
- Masking
- None
Eligibility Criteria
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients undergoing routine calcium scoring CT at facilities at the University of Pennsylvania
Exclusion Criteria
- •Patients found to have no coronary calcium on full dose FBP reconstructions
Outcomes
Primary Outcomes
Calcium score
Time Frame: immediate
Calcium score compared to FBP full dose recon
Secondary Outcomes
- Risk stratification(immediate)
Investigators
Harold Litt, MD, PhD
Associate Professor of Radiology
University of Pennsylvania
Study Sites (2)
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