Resistance Training With Blood Flow Restriction

Not Applicable

Active, not recruiting

• Conditions: Healthy
• Interventions: Other: Regular training type 1; Other: Regular training type 2; Other: Blood flow restriction

• Registration Number: NCT05863039
• Lead Sponsor: University of Oklahoma

Brief Summary

Blood flow restriction associated with resistance training is suggested to potentiate increases in muscular strength and hypertrophy. This study will compare the effects of resistance training associated with blood flow restriction with a regular resistance training program. Findings of this project will provide important information regarding a promising intervention to potentiate muscle performance.

Detailed Description

The purpose of this study is to determine alterations in motor unit behavior of the tibialis anterior muscles after a resistance exercise program associated with blood flow restriction. Our working hypothesis is that blood flow restriction to working muscles will induce greater changes in muscle activation, lean mass and muscle size compared with a training at same intensity without blood flow restriction.

Study Timeline

• Study Start: 2022-11-01
• Study First Submitted: 2023-04-17
• Study First Submitted QC: 2023-05-08
• Study First Posted: 2023-05-17
• Status Verified: 2024-12
• Last Update Submitted: 2024-12-05
• Last Update Posted: 2024-12-06
• Primary Completion: 2025-05-31
• Study Completion: 2026-09-30

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Not provided

Exclusion Criteria

• presence of neurological diseases,
• presence of metal implants or joint replacement
• any restriction to perform physical activity
• pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group 2	Regular training type 1	Conventional strength training using high loads
Group 3	Regular training type 2	Conventional strength training using low loads
Group 1	Blood flow restriction	Strength training associated with blood flow restriction

Primary Outcome Measures

Name	Time	Method
Force	10 sessions (up to 6 weeks)	Force of the lower leg muscles using a custom made ergometer

Secondary Outcome Measures

Name	Time	Method
Body composition	Start and end of the protocol	dual x-ray absorptiometry (DEXA) will be used to assess body composition

Trial Locations

Locations (1)

University of Oklahoma; 🇺🇸 Norman, Oklahoma, United States