Vitamin D Supplementation and Respiratory Index of Severity in Children (RISC) in Pneumonia
- Registration Number
- NCT02936895
- Lead Sponsor
- Hormozgan University of Medical Sciences
- Brief Summary
Childhood deaths from pneumonia is almost 2000 times higher in developing countries than in developed countries. In 1970, pneumonia was responsible for 9% of all deaths in children under 5 years. This rate was 2% in 2007.
Some studies have shown that supplementing with vitamin D reduces disease of the respiratory tract infection. Some other studies have shown anti-inflammatory effect of vitamin D in cell lines. Studies about the role of vitamin D supplementation in pneumonia in children are inadequate to conclude about its role.
The aim of this study is to determine the efficacy of vitamin D supplementation in Respiratory Index of Severity in Children (RISC) hospitalized clinical outcomes of hospitalized patients with community-acquired pneumonia.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 100
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Vitamin D3 (Low dose) Vitamin D3 vitamin D at a dose of 50,000 IU per day for 2 days Placebo Placebo Placebo (same size and shape) for 2 days
- Primary Outcome Measures
Name Time Method Respiratory Index of Severity in Children (RISC) through study completion, an average of 4 days For determining severity of pneumonia, RISC (Respiratory Index of Severity in Children) scoring system was used, including oxygen saturation, chest retraction, wheezing and refusal to feed, and also contains standards growth (weight for age).
- Secondary Outcome Measures
Name Time Method Duration of hospitalization through study completion, an average of 4 days Duration of hospitalization of the patient
Trial Locations
- Locations (1)
Shahid Mohammadi hospital
🇮🇷Bandar Abbas, Hormozgan, Iran, Islamic Republic of