Application of Artificial Intelligence on the Diagnosis of Helicobacter Pylori Infection and Premalignant Gastric Lesion: A Multihospital Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Helicobacter Pylori Infection
- Sponsor
- National Taiwan University Hospital
- Enrollment
- 2000
- Locations
- 1
- Primary Endpoint
- Sensitivity to detect premalignant gastric lesions
- Status
- Recruiting
- Last Updated
- 10 months ago
Overview
Brief Summary
The aim of this diagnostic accuracy study is to evaluate the application of artificial intelligence on the diagnosis of Helicobacter pylori infection and premalignant gastric lesions based on upper endoscopic images. We use techniques of artificial intelligence to analyze the correlation between endoscopic images and urea breath test results/histopathological results.
Detailed Description
This study had invited patients to undergo urea breath test, upper gastrointestinal endoscopy, and histology examination. The study will collect their tests results, upper gastrointestinal endoscopy images, and histopathological results. Artificial intelligence techniques will be used to analyze the correlation between endoscopic images and urea breath test results/histopathological results. We aim to establish a telemedicine system to assist clinicians in diagnosing Helicobacter pylori infection and detecting premalignant gastric lesion using upper endoscopic images. The system will be implemented as a telemedicine service system in the rural areas, for example Matsu Islands. The baseline histological predictions will be linked to the newly incident gastric cancer.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Scheduled urea breath test and endoscopy
Exclusion Criteria
- •History of gastric surgery
Outcomes
Primary Outcomes
Sensitivity to detect premalignant gastric lesions
Time Frame: Up to 5 years
Outcomes include the atrophic gastritis, intestinal metaplasia, and Helicobacter pylori infection
Secondary Outcomes
- Specificity to exclude premalignant gastric conditions(Up to 5 years)