Optimization of 99mTc-Sestamibi Activities in SPECT/CT Myocardial Perfusion Imaging

Completed

• Conditions: Coronary Heart Disease

• Registration Number: NCT05146323
• Lead Sponsor: Centre Hospitalier Régional Metz-Thionville

Brief Summary

This work suggests a methodology to adapt the injected radionuclide activity to the level of attenuation of each patient. The investigators propose a dose reduction adapted to the patient's weight, with no significant degradation of the image quality, in order to improve patients and staff radioprotection, standardize the image quality for easier clinical interpretation, and lead to radiopharmaceutical saving in the context of myocardial perfusion Imaging.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-02-11
• Primary Completion: 2021-06-30
• Study Completion: 2021-09-24
• Status Verified: 2021-11
• Study First Submitted: 2021-11-23
• Study First Submitted QC: 2021-11-23
• Last Update Submitted: 2021-11-23
• Study First Posted: 2021-12-06
• Last Update Posted: 2021-12-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 294

Inclusion Criteria

• Patient underwent stress-test 99 mTc-Sestamibi SPECT/CT myocardial perfusion Imaging on a Siemens Intevo Bold Anger camera with the cardiofocal SmartZoom® collimator

Exclusion Criteria

• None

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of counts	Day 1	Number of counts in the myocardial region of interest

Secondary Outcome Measures

Name	Time	Method
Clinical evaluation	Day 1	Medical evaluation of image quality, in order to establish a correlation between the myocardial signal level and the clinical image quality

Trial Locations

Locations (1)

CHR Metz Thionville; 🇫🇷 Metz, Moselle, France