SOM230 Graves Orbitopathy pilot trial

Withdrawn

• Conditions: Graves Orbitopathy/Eye Disease; 10043739; 10003816

• Registration Number: NL-OMON38562
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Withdrawn
• Sex: Not specified
• Target Recruitment: 12

Inclusion Criteria

-moderate * severe GO
-corticosteroids contraindicated due to diabetes mellitus (see below), severe
osteoporosis, heart failure, psychosis, infectious diseases or other clinical relevant
comorbidities
-corticosteroids refused by patients
-age > 18

Exclusion Criteria

-inability/refusal to give informed consent
-pregnancy
-GO (dysthyroid optical neuropathy) necessitating high dose steroids or acute
decompression
-abnormal thyroid function (defined as TSH >4.0 mU/l or FT4 <10 or >21 pmol/l)
-pregnancy
-drug abuse and smoking.

Study & Design

• Study Type: Interventional
• Study Design: Not specified