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临床试验/NCT07671300
NCT07671300尚未招募不适用

Evaluating Superficial Vein Thrombosis in the Emergency Department.

Dr. Kerstin de Wit1 个研究点 分布在 1 个国家目标入组 400 人开始时间: 2026年7月15日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
400
试验地点
1
主要终点
Superficial vein thrombosis, deep vein thrombosis and no thrombosis

研究概览

简要总结

Superficial vein thrombosis (SVT) occurs when blood in a vein directly under the skin clots. SVT causes vein tenderness, pain, and skin discolouration. Over time, the vein hardens into a firm, nontender, easily palpable lump. SVT commonly occurs in the veins of the leg. Each year, 1 per 1000 people over the age of 18 have SVT. SVT is painful but usually gets better within a month. Four in 100 people with SVT develop progressively worse blood clotting involving the deep veins or lungs.

If a deep vein clot in the leg occurs it can cause permanent disability with post-thrombotic syndrome (long-term leg pain and swelling) and reduced quality of life. If a pulmonary embolism occurs it may cause chest pain, breathlessness, pulmonary hypertension, psychological distress, and potentially death. Guidelines tell doctors to use ultrasound scanning to decide whether SVT needs treatment with a blood thinner or not. Blood thinners prevent the clot from worsening.

Many people who have SVT go to the emergency department. Scanning is limited to the daytime so often people have multiple trips to the emergency department for their scan and they spend many hours waiting for a doctor to see them. Our research group developed simple ways to limit the need for scans for other types of blood clots, like blood clots in the lungs or in the deep veins. We use a simple blood test called D-dimer. We believe we may be able to use D-dimer to help limit the need for SVT scanning.

This is an exploratory study to document what happens to patients tested for SVT in the emergency department, and to see if the D-dimer blood test might be useful in reducing scans. Our research group will review the emergency department charts for patients who came to the emergency department with SVT. Our results will tell us whether further studies would be helpful.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Aged ≥ 18
  • Tested for superficial vein thrombosis in the emergency department or urgent care centre
  • Patients tested for SVT at all sites, including arms, legs and torso

排除标准

  • Patient opted out of research at the participating site
  • Patient included in the study in the last 90 days

研究组 & 干预措施

Emergency department patients tested for superficial vein thrombosis

干预措施: D-dimer (Diagnostic Test)

结局指标

主要结局

Superficial vein thrombosis, deep vein thrombosis and no thrombosis

时间窗: During index testing

SVT will be classified as a) situated within 3 cm of the deep vein junction, b) ≥ 5 cm in length and \> 3 cm from the deep vein junction, and c) SVT \< 5 cm in length and \> 3 cm from the deep vein junction. Diagnosis of deep vein thrombosis and the finding of no thrombosis will be reported.

次要结局

  • The secondary outcomes will the subsequent development of recurrent SVT, SVT propagation, deep vein thrombosis, pulmonary embolism, or death from pulmonary embolism among patients diagnosed with SVT at the index visit.(90 days)

研究者

发起方
Dr. Kerstin de Wit
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Dr. Kerstin de Wit

Professor

Queen's University

研究点 (1)

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