An investigation into whether the way potato is prepared, and what it is eaten with, affects the blood glucose response to its consumption, in people with type 2 diabetes

Not Applicable

Completed

• Conditions: Type 2 diabetes; Nutritional, Metabolic, Endocrine; Type 2 diabetes mellitus

• Registration Number: ISRCTN67897032
• Lead Sponsor: niversity of Surrey

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-08-12
• Study Completion: 2022-10-11
• Last Update Posted: 10 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

1. Patients with a diagnosis of type 2 diabetes >6 months
2. Males and females
3. Aged 18-70 years
4. Ability to understand English (to provide informed consent)

Exclusion Criteria

1. Use of insulin and GLP-1 analogues
2. History of gastroparesis or gastric surgery
3. Coeliac disease/wheat intolerance
4. Irritable bowel syndrome
5. HbA1c >75 mmol/mol
6. Pregnancy/breastfeeding
7. Excess alcohol intake
8. Glucose-lowering drug dosage adjustment within the previous month
9. Antibiotics in the last 3 months

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
At each visit using blood test:<br>1. Incremental area under the 3 h glucose response curve (IAUC). Sample timepoints are 0, 15, 30, 45, 60, 75, 90, 120 and 180 min.

Secondary Outcome Measures

Name	Time	Method
At each visit using blood test:<br>1. Incremental area under the 3 h insulin response curve (IAUC). Sample timepoints are 0, 15, 30, 45, 60, 75, 90, 120 and 180 min.<br>2. Peak glucose. <br>3. Peak insulin. <br>4. Time-to-peak glucose. <br>5. Time-to-peak insulin.<br>6. Matsuda Index.<br>7. Insulinogenic index.