The Influence of glycemic control on periodontal parameters in type II diabetics

Not Applicable

Conditions: K05.2
K05.3
E11.9
Acute periodontitis
Chronic periodontitis

Registration Number: DRKS00028168

Lead Sponsor: niversitätklinkum Freiburg, Klinik für Zahnerhaltunskunde und Parodontologie

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 50

Inclusion Criteria

Patients with chronically elevated long-term blood glucose levels, diabetes mellitus type 2 HbA1c = 8 %, periodontitis stage I-IV

Exclusion Criteria

Patients requiring acute treatment (e.g. periodontal abscess) or undergoing active dental treatment (e.g. periodontal therapy), smokers, severe general diseases (tumor diseases, palliative therapies), cortisone therapy, antibiotic therapy up to 6 months before study participation, pregnancy, and breastfeeding.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Periodontal Inflamed Surface Area (PISA)

Secondary Outcome Measures

Name	Time	Method
Probing depths (ST) measured with a calibrated probe (Aeskulap, DB764R), clinical attachment level, recessions, bleeding on probing, degrees of looseness, oral hygiene indices (Sillness & Löw, Löe & Sillness), general physical findings (height, weight, blood pressure, pulse, abdominal circumference), laboratory values (HbA1c, fasting blood glucose, creatinine, sodium, potassium, MDRD, GPT, GOT, GGT, triglycerides, total cholesterol, LDL cholesterol, HDL cholesterol, microalbumin), nutrition questionnaire (RKI DEGS questionnaire), questionnaire on oral health-related quality of life (OHIP-G 14). 1. measurement at the beginning of blood glucose control with medication, 2. measurement after 3 months