NL-OMON56926尚未招募不适用
Influence of flucloxacillin treatment on plasma concentration of CYP - and UGT-substrate drugs. - Flucloxacillin interaction study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Aged >=18 years
- •- Treated with >=6 grams/24h flucloxacillin iv (or equivalent dose in case of
- •renal impairment) for an intended duration of at least 10 days.
- •- Concomitant treatment with at least one of the following substrate drugs at
- •the moment of patient selection: diclofenac, metoprolol, oxycodone extended
- •release tablet, pantoprazole or paracetamol.
- •- Written informed consent.
排除标准
- •- Concomitant use of specific CYP-, UGT- and P-gp inducers and inhibitors (see
- •table S1 in the supplementary material of the study protocol).
- •- Pregnancy
- •- Dialysis patients
- •- Dementia
- •- IC-admission
研究者
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