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MULTICENTER PROBE STUDY-3; COMPARISON OF THE EFFECTS OF ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS

Not Applicable
Conditions
Hypertension
Registration Number
JPRN-UMIN000012767
Lead Sponsor
Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Department of Medicine and Clinical Sciences,
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
100
Inclusion Criteria

Not provided

Exclusion Criteria

The patients with 1) severe renal dysfunction (Cr > 2.0 mg/dl) 2) severe hepatic dysfunction (AST or ALT > 100IU/l) 3) the history of severe side effect of ARBs 4) pregnancy or lactation 5) malignancy or other poor-prognosis disease 6) those who are considered inappropriate by physician

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change in MCP-1, MDA-LDL, Pentraxin-3, hs-CRP
Secondary Outcome Measures
NameTimeMethod
Change in the clinic and home blood pressure, renal function(serum creatinine, uric acid, pottasium, eGFR), Lipids(LDL-C, HDL-C, T.cho), U-Alb/Cr
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