Effect of S (+) ketamine on the release of proinflammatory cytokines

Not Applicable

Recruiting

• Conditions: Urological and Genital Diseases; release of cytokines; Anaesthesia

• Registration Number: PACTR201510001293646
• Lead Sponsor: Cairo University hospitals, faculty of medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-10-04
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Male
• Target Recruitment: 60

Inclusion Criteria

ASA physical status I¿II,
aged 45-65 years old
scheduled for radical cystectomy under combined epidural general anesthesia

Exclusion Criteria

ASA physical status > ¿I,
morbid obesity (body mass index > 35), pre-existing neurological or psychiatric disorders,
chronic drug abuse,
the use of drugs affecting immunity as chemotherapy or hormonal therapy, uncontrolled diabetics,
renal,
hepatic,
hypertensive patients,
contraindication for epidural catheter insertion,
hypersensitivity for any anesthetics or drug used.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
release of proinflammatory cytokines

Secondary Outcome Measures

Name	Time	Method
hemodynamics, pain relief, PONV