Pulmonary Rehabilitation in Asthma Control

Not Applicable

Completed

• Conditions: Asthma
• Interventions: Other: Exercise

• Registration Number: NCT03227341
• Lead Sponsor: Izmir Katip Celebi University

Brief Summary

The investigators compared the effectiveness of pulmonary rehabilitation program on asthma control in patients with uncontrolled and partially controlled asthma.

Detailed Description

Asthma treatment is not only medical, it also requires a comprehensive care including nonpharmacological treatment. Pulmonary rehabilitation represents the most important part of the comprehensive care. The investigators aimed to evaluate the efficacy of pulmonary rehabilitation in patients with uncontrolled and partially controlled asthma.

Asthma patients referred to pulmonary rehabilitation (PR) unit were classified according to asthma control test; as partially controlled patients (Group 1), and as uncontrolled patients (Group 2). All patients received of a 8 week pulmonary rehabilitation program. Asthma control tests, pulmonary function tests, arterial blood gases analysis, dyspnea perception, quality of life, exercise capacity, anxiety and depression assessments were performed before and after pulmonary rehabilitation.

Study Timeline

• Study Start: 2013-01-01
• Primary Completion: 2017-01-01
• Study Completion: 2017-01-01
• Status Verified: 2017-07
• Study First Submitted: 2017-07-20
• Study First Submitted QC: 2017-07-21
• Last Update Submitted: 2017-07-21
• Study First Posted: 2017-07-24
• Last Update Posted: 2017-07-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

• Asthmatic patients referred from the outpatient clinic to Pulmonary Rehabilitation unit was confirmed according to GINA guidelines

Exclusion Criteria

• If the initial diagnosis cannot be confirmed, the patient excluded from the study
• Patients were under medical treatment of -6 months and considered clinically stable.
• Patients with cardiovascular, other lung diseases (pneumoconiosis, pulmonary tuberculosis, interstitial lung disease), or musculoskeletal diseases that would impair exercise training were excluded from the study.
• Also subjects with lack of motivation, poor compliance (not attending the program more than 2 times) or having transport problems were excluded from the study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
patients with uncontrolled asthma.	Exercise	8 week pulmonary rehabilitation program
patients with partially controlled asthma	Exercise	8 week pulmonary rehabilitation program

Primary Outcome Measures

Name	Time	Method
Asthma control test score	4 weeks	A test measured the control of asthma

Secondary Outcome Measures

Name	Time	Method
Exercise capacity	6 minute	Six minute walk test
Arterial Blood Gas	1 hour	PaO2, PaCO2, SaO2
Dyspnea	1 year	MMRC Dyspnea Scale
Quality of Life	1 year	St. George Respiratory Questionnaire
Pulmonary Function Test	1 hour	FEV1, FVC, DLCO
Anxiety and Depression	1 week	Hospital Anxiety and Depression Scale