EUCTR2011-002928-41-AT进行中（未招募）1 期
Characterization of humoral and cellular immunity for tick-borne encephalitis (TBE) vaccination in allogeneic blood and marrow graft recipients: a pilot study
Med. Uni. Wien, Klinik für Innere I0 个研究点目标入组 52 人开始时间: 2012年11月23日最近更新:
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 52
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Adult patients =18 years who
- •-had undergone an allogeneic HSCT 11 to 13 months ago or
- •-healthy volunteers without previous TBE vaccination
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 52
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range 0
排除标准
- •-Previous TBE vaccination following HSCT
- •-HSCT patients with extremely severe acute graft versus host disease (receiving prednisone >0.5 mg/kg bodyweight as part of a combination therapy or a three agent immunosuppressive treatment)
- •-Previous TBE virus infection, previous dengue virus infection or vaccination against yellow fever or Japanese encephalitis
- •-Any acute febrile illness in the 2 weeks prior to or at the time of enrolment
- •-A history of severe allergic reactions or anaphylaxis after vaccination
- •-If female, are pregnant or lactating
- •-If belonging to the healthy control group are immunosuppressed
研究者
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