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临床试验/CTRI/2025/07/091878
CTRI/2025/07/091878尚未招募不适用

Study of Epilepsy through Miasmatic Approach and Its Homoeopathic Management.

C D Pachchigar College of Homoeopathic Medicine and Hospital1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年8月5日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
30
试验地点
1
主要终点
To assess the role of Homoeopathic Medicines selected through

研究概览

简要总结

6 BRIEF RESUME OF INTENDED WORK

6.1 NEED FOR STUDY

A healthy human being is a balanced entity where physical, mental, and emotional well-being coexist in harmony. The brain as the control center of the body plays a crucial role in maintaining homeostasis by regulating voluntary and involuntary functions, emotions, cognition, and consciousness. A well-functioning brain ensures proper coordination between the nervous system and other organ systems allowing an individual to lead a productive life.

The brain is made up of billions of nerve cells or neurons that communicate with each other through synapses. The brain is part of the central nervous system CNS along with the spinal cord. The brain is responsible for many functions including controlling heart rate mood and body temperature. The brain is divided into left and right hemispheres and each hemisphere has four lobes. Due to some reasons when healthy normal brain experiences hyper electrical activity a typical clinical picture is produced which is called epilepsy.

Epilepsy is a neurological disorder characterized by recurrent seizures. These seizures can vary widely in their presentation and severity ranging from brief lapses of attention to full body convulsions. Understanding the underlying causes of epilepsy such as genetic factors brain injury or structural abnormalities is essential for effective management.

The miasmatic approach to disease rooted in homeopathy considers chronic diseases as arising from underlying constitutional weaknesses or inherited predispositions. Epilepsy a neurological disorder characterized by recurrent seizures is often studied through conventional medical lenses focusing on genetic metabolic or structural causes. However from a homeopathic perspective understanding epilepsy through miasmatic theory can offer deeper insights into its chronic nature underlying predispositions and individualized treatment strategies.

Reasons to Study Epilepsy Miasmatically

1 Identifying constitutional predisposition 2 Holistic individualized treatment 3 Understanding suppression and disease progression 4 Complementary insights for chronic cases

There have been studies and case reports in homeopathic literature that explore epilepsy within the therapeutic framework. However no research has been done correlating epilepsy with miasmatic consideration.

6.2 REVIEW OF LITERATURE

Earlier the Babylonians and Egyptians had documented epilepsy but attributed it to divine or demonic causes. Hippocrates was the first to describe epilepsy as a brain disorder rejecting the belief that it was caused by supernatural forces. This laid the foundation for modern understanding of epilepsy as a medical condition.

An epileptic seizure is a transient occurrence of signs and symptoms due to abnormal excessive or synchronous neuronal activity in the brain. Epilepsy is a disorder of the brain characterized by an enduring predisposition to generate epileptic seizures and by the neurobiological cognitive psychological and social consequences.

According to the International League Against Epilepsy ILAE at least two unprovoked seizures occurring more than 24 hours apart or one seizure with a high risk of recurrence or a diagnosis of an epilepsy syndrome is considered epilepsy.

Epilepsy affects over 50 million people worldwide. Sudden unexpected death in epilepsy SUDEP accounts for 8 to 17 percent of epilepsy-related deaths.

Homeopathy aims to identify and remove both exciting and maintaining causes to treat epilepsy holistically. Medicines are administered in minimum doses and selected based on a detailed symptom picture.

Hahnemann emphasized individualization over disease naming. Saxton argued epilepsy is a result of deep miasmatic disturbance. Ramakrishnan noted allopathic medicine provides palliation not cure while homeopathy may bring about deep constitutional change.

Hahnemann stated miasms are inherited and do not spread solely via contact. He identified congenital miasms in syphilis gonorrhea and Psora which he believed nearly everyone carries.

Roberts highlighted miasms as destructive forces causing mental and physical illness. Hahnemann insisted that identifying the exciting cause and chronic history is essential to find the fundamental cause usually miasmatic.

In ICD-11 epilepsy is classified under code 8A60.

Classification and Causes

Classification:

FOCAL

Awareness/Impaired Awareness

Motor Onset:

Automatisms

Atonic

Clonic

Epileptic Spasm

Hyperkinetic

Myoclonic

Tonic

Non-Motor Onset:

Autonomic

Behavior Arrest

Cognitive

Emotional

Sensory

Other:

Focal to Bilateral Tonic Clonic

GENERALIZED

Motor:

Tonic-Clonic

Clonic

Tonic

Myoclonic

Myoclonic Tonic-Clonic

Myoclonic Atonic

Atonic

Epileptic Spasm

Non-Motor (Absence):

Typical

Atypical

Myoclonic

Eyelid Myoclonia

UNKNOWN

Motor:

Tonic-Clonic

Epileptic Spasm

Non-Motor:

Behavior Arrest

Unclassified

Causes of Epilepsy :

Idiopathic: 66%

Vascular disease: 11%

Congenital: 8%

Trauma: 5%

Tumors: 4%

Neurodegenerative disease: 3%

Infectious disease: 3%

Clinical Features

Focal Seizure Impaired consciousness Blank stare blinking lip smacking clothes picking Postictal drowsiness bizarre behavior motor activity

Generalized Tonic-Clonic Seizure Sudden loss of consciousness Tonic phase body becomes rigid breathing stops Clonic phase rapid jerking incontinence salivation Postictal confusion headache drowsiness

Absent Seizure Short lapse of consciousness lasting 10–30 seconds Staring loss of tone multiple times a day

Myoclonic Seizure Rhythmic jerking of limbs or trunk

Clonic Seizure Alternating muscle contractions and relaxation

Tonic Seizure Sustained muscle contraction

Atonic Seizure Sudden loss of posture common in children

Diagnosis

Blood tests EEG CT scan MRI PET SPECT Neuropsychological tests MEG

Homeopathic Approach

Epilepsy as a chronic miasmatic disorder needs holistic care. Homeopathy based on similia similibus curentur addresses both symptoms and root causes through constitutional treatment.

Homeopathy requires detailed case-taking considering history symptoms and inherited tendencies. Medicines are selected based on physical mental and emotional characteristics and miasmatic influences.

In new cases without long-term allopathic use homeopathy has shown strong potential. It is safe across age groups and free of side effects when prescribed correctly.

Miasmatic Correlation

Psoric epilepsy - Functional overactivity emotional triggers hypersensitivity Sycotic epilepsy - Suppressed infections hormonal issues structural lesions Syphilitic epilepsy - Degenerative neurological decline inherited disorders

Most cases have mixed miasmatic origins needing customized long-term treatment.

Thorough evaluation including seizure type aura triggers and systemic factors is essential. Success depends on remedy selection aligned with miasmatic and constitutional profile.

6.3 OBJECTIVES OF STUDY

1 To assess the role of homeopathic medicines selected through the miasmatic approach in epilepsy 2 To identify predominant miasm associated with epilepsy 3 To assess changes in severity and frequency of seizures before and after miasmatic treatment

7 MATERIALS AND METHODS

7.1 SOURCE OF DATA OPD of C D Pachchigar Homeopathic College and Hospital, peripheral centers and regular camps. Case taking as per aphorisms 83 to 104 from Organon of Medicine.

7.2 MATERIAL Textbooks like API and Davidson’s Principles and Practice of Medicine, Organon of Medicine, Materia Medica, repertory, related software and resources

7.3 METHOD OF COLLECTION OF DATA Study type: Experimental Study design: Prospective Population: Patients from C D Pachchigar Homoeopathic Hospital and peripheral OPDs Sample size: 30 patients Sampling technique: Non-probability purposive sampling Duration: 9 months

Inclusion Criteria 1 Diagnosed epilepsy cases 2 Age 2 years and above 3 All socioeconomic status 4 Both sexes

Exclusion Criteria 1 Non-compliant or unreliable patients 2 Pregnant or lactating women 3 Children below 2 years 4 Surgical epilepsy cases 5 Severe psychiatric or progressive neurological disorders

Data Analysis Improved: Marked clinical reduction in symptoms Not Improved: No significant changes Left Treatment: Patients who discontinue follow-up before advised

7.4 INVESTIGATIONS REQUIRED Diagnosis will be based on clinical history. Special investigations will be done if needed.

7.5 ETHICAL CLEARANCE Yes

8 BIBLIOGRAPHY

1 Epilepsy Society https://epilepsysociety.org.uk 2 Hippocrates The Sacred Disease https://classics.mit.edu/Hippocrates/sacred.html 3 API Textbook of Medicine 12th Edition 4 Hahnemann S Organon of Medicine 6th Edition 5 Saxton J Miasms as Practical Tools 6 Ramakrishnan AU Homeopathic Approach to Cancer 7 Hahnemann S The Chronic Diseases 8 Roberts HA Principles and Art of Cure by Homoeopathy 9 WHO International Classification of Diseases ICD-11 https://icd.who.int/en 10 Davidson’s Principles and Practice of Medicine 24th Edition

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
2.00 Year(s) 至 99.00 Year(s)(—)
性别
All

入选标准

  • 1 Already diagnosed cases of Epilepsy.
  • 2 Patients of all the socio-economical status will be included.

排除标准

  • 1 Non-Compliant or Unreliable patients.
  • 2 Pregnant or Lactating women.
  • 3 Patient undergoing recent or planned surgical interventions for Epilepsy.
  • 4 Patients with severe Psychiatric Co-morbid conditions, Structural or Progressive Neurological disorders and Acute Symptomatic Epilepsy will be excluded.

结局指标

主要结局

To assess the role of Homoeopathic Medicines selected through

时间窗: 6 months

Miasmatic approach in Epilepsy.

时间窗: 6 months

次要结局

  • To identify predominant Miasm associated with Epilepsy.(6 months)

研究者

发起方
C D Pachchigar College of Homoeopathic Medicine and Hospital
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Dr Mayurkumar Mukeshbhai Rathod

C D Pachchigar College of Homoeopathic Medicine and Hospital

研究点 (1)

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