utility of transvaginal ultrasonography in detecting endometrial hyperplasia in premenopausal and postmenopausal women
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Diagnostic Accuracy of TVUS for Endometrial Hyperplasia
研究概览
简要总结
Transvaginal ultrasonography (TVUS) plays a significant role in diagnosing endometrial hyperplasia in pre- and post-menopause women.
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Accuracy: TVUS showed an accuracy of 88.25% in premenopause women and 100% in postmenopause women ¹.
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Sensitivity and Specificity: The sensitivity and specificity of TVUS in diagnosing endometrial hyperplasia were 90.7% and 84% in premenopause women, respectively ¹.
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Positive and Negative Predictive Values: The positive predictive value (PPV) and negative predictive value (NPV) of TVUS were 90.7% and 84% in premenopause women, respectively ¹.
TVUS is a valuable diagnostic tool for evaluating abnormal uterine bleeding (AUB) and detecting endometrial hyperplasia, particularly in postmenopause women ¹. The high accuracy and sensitivity of TVUS make it an essential screening method in gynecological practice.
Overall, TVUS is a reliable diagnostic tool for detecting endometrial hyperplasia in pre- and post-menopause women, especially when used in conjunction with other diagnostic methods.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 35.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- Female
入选标准
- •Presence of symptoms suggestive of endometrial hyperplasia (e.g., abnormal uterine bleeding, pelvic pain) in Pre and post menopausal women who can undergo TVUS examination.
排除标准
- •Pregnancy or suspected pregnancy
- •Known or suspected endometrial cancer
- •Previous hysterectomy or endometrial ablation
- •Current or recent (within 6 months) use of hormone replacement therapy (HRT)
- •History of pelvic radiation therapy
- •Inability to undergo TVUS examination due to medical or physical limitations
- •Known allergy to ultrasound gel or other materials used during TVUS examination.
结局指标
主要结局
Diagnostic Accuracy of TVUS for Endometrial Hyperplasia
时间窗: 4 WEEKS AND 8 WEEKS.
The main outcome is assessing how accurately transvaginal ultrasonography (TVUS) can detect endometrial hyperplasia in premenopausal and postmenopausal women.
时间窗: 4 WEEKS AND 8 WEEKS.
次要结局
- Optimal Endometrial Thickness Thresholds: Determining appropriate endometrial thickness cut-off values for diagnosing hyperplasia in both premenopausal and postmenopausal groups.(Morphological Patterns on TVUS: Identifying specific endometrial patterns (e.g., diffuse thickening or irregular contours) associated with hyperplasia, aiding in distinguishing between types of hyperplasia.)
- TO KNOW THE THICKNESS(8 WEEKS)
研究者
dr srungavarapu revathi
shri b.m.patil medical college hospital and research centre