utility of transvaginal ultrasonography in detecting endometrial hyperplasia in premenopausal and postmenopausal women
Overview
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- DrRevathi
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Diagnostic Accuracy of TVUS for Endometrial Hyperplasia
Overview
Brief Summary
Transvaginal ultrasonography (TVUS) plays a significant role in diagnosing endometrial hyperplasia in pre- and post-menopause women.
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Accuracy: TVUS showed an accuracy of 88.25% in premenopause women and 100% in postmenopause women ¹.
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Sensitivity and Specificity: The sensitivity and specificity of TVUS in diagnosing endometrial hyperplasia were 90.7% and 84% in premenopause women, respectively ¹.
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Positive and Negative Predictive Values: The positive predictive value (PPV) and negative predictive value (NPV) of TVUS were 90.7% and 84% in premenopause women, respectively ¹.
TVUS is a valuable diagnostic tool for evaluating abnormal uterine bleeding (AUB) and detecting endometrial hyperplasia, particularly in postmenopause women ¹. The high accuracy and sensitivity of TVUS make it an essential screening method in gynecological practice.
Overall, TVUS is a reliable diagnostic tool for detecting endometrial hyperplasia in pre- and post-menopause women, especially when used in conjunction with other diagnostic methods.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 35.00 Year(s) to 80.00 Year(s) (—)
- Sex
- Female
Inclusion Criteria
- •Presence of symptoms suggestive of endometrial hyperplasia (e.g., abnormal uterine bleeding, pelvic pain) in Pre and post menopausal women who can undergo TVUS examination.
Exclusion Criteria
- •Pregnancy or suspected pregnancy
- •Known or suspected endometrial cancer
- •Previous hysterectomy or endometrial ablation
- •Current or recent (within 6 months) use of hormone replacement therapy (HRT)
- •History of pelvic radiation therapy
- •Inability to undergo TVUS examination due to medical or physical limitations
- •Known allergy to ultrasound gel or other materials used during TVUS examination.
Outcomes
Primary Outcomes
Diagnostic Accuracy of TVUS for Endometrial Hyperplasia
Time Frame: 4 WEEKS AND 8 WEEKS.
The main outcome is assessing how accurately transvaginal ultrasonography (TVUS) can detect endometrial hyperplasia in premenopausal and postmenopausal women.
Time Frame: 4 WEEKS AND 8 WEEKS.
Secondary Outcomes
- Optimal Endometrial Thickness Thresholds: Determining appropriate endometrial thickness cut-off values for diagnosing hyperplasia in both premenopausal and postmenopausal groups.(Morphological Patterns on TVUS: Identifying specific endometrial patterns (e.g., diffuse thickening or irregular contours) associated with hyperplasia, aiding in distinguishing between types of hyperplasia.)
- TO KNOW THE THICKNESS(8 WEEKS)
Investigators
dr srungavarapu revathi
shri b.m.patil medical college hospital and research centre