Efficacy of Ninjin'yoeito, a representative Kampo (Japanese herbal medicine) formula for dual deficiency of qi and blood, in oral frailty: Observational study
Not Applicable
- Conditions
- Oral frailty
- Registration Number
- JPRN-UMIN000039882
- Lead Sponsor
- Department of Otolaryngology, Head and Neck Surgery Kanazawa University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 13
Inclusion Criteria
Not provided
Exclusion Criteria
1. Patients having taking Kampo formula with supplemental effect in the post 2 weeks. 2. Smoker in the post 1 year. 3. Patients having past history or suspicion of aldosteronism, myopathy, or hypokalemia. 4. Patients diagnosed as having the following: severe heart disease, kidney disease, or endocrine metabolic disease. 5. Patients considered inappropriate for this trial by the physicians-in-charge.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Score of subjective symptoms in questionnaire
- Secondary Outcome Measures
Name Time Method 1. Severity score of symptoms: Physical strength decline after illness or operation, fatigue/ malaise, loss of appetite, night sweat, coldness of hands and feet, or anemia. 2. Moitening of oral mucosa 3. RSST (Repetitive saliva swallowing test) 4. VAS (Visual Analogue Scale) of taste 5. Peripheral blood flow and blood flow velocity 6. Function of NK (Natural Killer) cell