Efficacy and Safety of two artificial saliva base polymers containing with 0.1% pilocarpine for Treatment of xerostomia: A Randomized Clinical Trial

Phase 1

Recruiting

• Conditions: xerostomia or dry mouthhyposalivation; xerostomia; hyposalivation

• Registration Number: TCTR20200902001
• Lead Sponsor: euroscience Research and Development Group, Khon Kaen University, Khon Kaen, Thailand

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-09-02
• Study Completion: 2021-02-28
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Having questionnaires xerostomia inventory score more than 11

Exclusion Criteria

1.Pathologic oral lesion
2.Alcohol and caffeine consumption
3.Smoking
4.Sodium benzoate allergy
5.Pilocarpine allergy or having any contraindication

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
quanlity and quantity of saliva at 6 weeks Sialometry, saliva pH, buffer capacity of saliva

Secondary Outcome Measures

Name	Time	Method
safety after used artificial saliva at 6 weeks questionnaires